Ph.D., International School for Advanced Studies, Trieste Italy 1996
mRNA processing
mRNA splicing regulation
HIV-1 replication
Bcl apoptotic gene family regulation
Johns Hopkins University, Research Scientist, 2001-2003
University of Santa Cruz, CA, 1996-2001
Caputi,M., Freund,M. Kammler,S, and Schaal,H. A bidirectional SR protein dependent
exonic splicing enhancer regulates splice site-dependent Rev-mediated HIV-1 env gene expression.
J. Vir. 78, 6517-6526. (2004).
Zahler,A.M, Damgaard,C.K., Kjems,J. and Caputi,M. SC35 and hnRNPs A/B binding
to a juxtaposed ESE/ESS element regulates HIV-1 tat exon 2 splicing. J. Biol. Chem.,
279,10077-10084. (2004).
Giles,K.E., Caputi,M. and Beemon,K.L. Packaging and reverse transcription of snRNAs
by retroviruses may generate pseudogenes. RNA. 10,299-307. (2004).
Caputi,M., Kendzior,R.J. and Beemon,L.K. A nonsense mutation in the fibrillin-1 gene
of a Marfan syndrome patient induces NMD and disrupts an exonic splicing enhancer. Genes &
Dev., 16, 1754-1759. (2002).
Caputi,M. and Zahler,A.M., SR proteins and hnRNP H family members regulate the
splicing of the HIV-1 tev-specific exon 6D. EMBO J., 21, 845-855. (2002).
Caputi,M. and Zahler,A.M., Determination of the RNA Binding Specificity of the
Heterogeneous Nuclear Ribonucleoprotein (hnRNP) H/H’/F/2H9 Family. J. Biol. Chem.,
276, 43850-43859. (2001).