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Department of Basic Science
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Iragavarapu-Charyulu, Vijaya Dr.
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- B.A., University of Miami, Miami, Florida, 1975
- PhD., University of Miami School of Medicine, Miami, Florida, 1980
- BSMT, Florida Atlantic University, Boca Raton, Florida, 1998
- Tumor immunology
- Cytokine expression and transcriptional regulation during mammary tumorigenesis
- Chemokine/chemokine receptor expression in mammary tumor progression
- Matrix metalloproteinases (MMPs) and leukocyte trafficking by T cells
- Signaling events in T cells as they pertain to elevated levels of expression of chemokines and MMPs
- Florida Atlantic University, Dept of Medical Laboratory Sciences; Asst Professor, 1999-2002
- University of Miami, Instructor, 1995-1999
- University of Miami, Post Doctoral Fellow, 1993-1995
- Mount Sinai Medical Center (New York), Post Doctoral Fellow, 1980-1981
- Mary-Ellen handel-Fernandez, D. Ilkovitch, V. Iragavarapu-Charyulu, L.M. Herbert and D.M. Lopez. Decreased levels of both Stat 1 and Stat 3 in T lymphocytes from mice bearing mammary tumors. Anticancer Research, 29: 2051-58. (2009).
- Marta Torroella-Kouri, Risset Silvera, Dayron Rodriguez, Raul Caso, Alwi Shatry, Shannon Opiela, Dan Ilkovitch, Reto A. Schwendener, Vijaya Iragavarapu-Charyulu, Yoslayma Cardentey, Natasa Strbo, and Diana M. Lopez. Identification of a Subpopulation of Macrophages in Mammary Tumor-Bearing Mice That Are Neither M1 nor M2 and Are Less Differentiated. Cancer Research, 69 (11): 4800-09. (2009).
- Owen,J., Torroella-Kouri, M., Handel-Fernandez, M., and Iragavararpu-Charylulu, V. GM-CSF up-regulates the expression of CCL2 by T lymphocytes in mammary tumor-bearing mice. Int. Journal of Molecular Medicine, 20 (1): 129-135. (2007).
- Marta Torroella-Kouri, Xiaojing Ma, Giselle Perry, Milena Ivanova, Pedro J. Cejas, Jennifer L. Owen, Vijaya Iragavarapu-Charyulu and Diana M. Lopez. Altered NF-kB and C/EBP signaling pathways underlie the dysregulation of cytokines and receptor gene expression in macrophages of mammary tumor-bearing mice. Cancer Research, 65 (22): 10578-84. (2005).
- Owen, J., Lopez, D.M. and Iragavarapu-Charyulu, V. The expression of CCL2 by T lymphocytes of mammary tumor bearers: Role of tumor-derived factors. Cellular Immunology, 235: 122-135. (2005).
- Owen, J., Iragavarapu-Charyulu, V., and Lopez, DM. T cell-derived matrix metalloproteinase-9 in breast cancer: Friend or Foe? Breast Disease, 20: 145. (2004).
- Owen, J., Iragavarapu-Charyulu, V., Gunja-Smith, Z., Herbert, L., Grosso, J., and Lopez, D.M. Upregulation of Matrix metalloproteinase-9 in T lymphocytes of mammary tumor bearers: Role of tumor derived factors. J. Immunol. 171: 4340. (2003).
- Lopez, D.M., Charyulu, V., and Adkins, B. Influence of breast cancer on thymic function in mice. Journal of Mammary Gland Biology and Neoplasia. 17:28 (191-199). (2002).
- Sun, Q.L., Charyulu, V., Lobo, D., and Lopez, D.M. Role of thymic stromal cell dysfunction in the thymic involution of mammary tumor bearing mice. Anticancer Res. 22: 91-96. 2002
- Adkins, B., V. Charyulu, Q-L. Sun, D. Lobo, and D.M. Lopez. Early block in maturation is associated with thymic involution in mammary tumor bearing mice. Journal of Immunol., 164:5635-5640. (2000).
- Charyulu, V. and D.M. Lopez. Elevated GM-CSF levels in tumor bearing mice upregulate IL-6 production by B cells via a mechanism independent of TNF-?. Int J. of Oncol., 16:161-167. (2000).
- Charyulu, V., and D.M. Lopez. Abnormal binding pattern and composition of the NF-kB complex components are involved in increased TNF-? production by tumor bearers’ B cells. Int. J. Mol. Med., 3:411-416. (1999).
- Lopez, D.M., M.E. Handel-Fernandez, X. Cheng, V. Charyulu, M. DiNapoli, and C. Calderon. Cytokine production by lymphoreticular cells from mammary tumor bearing mice: The role of tumor-derived factors. Anticancer Res., 16:3923-3930.(1996).
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