Ph.D., George Washington University, Washington, D.C. 1991
The molecular genetics of eye diseases including age-related human
cataract and age-related macular degeneration.
National Eye Institute, NIH, Bethesda, MD;
Senior Staff Fellow, 1996-1997
Jules Stein Eye Institute, UCLA Medical School, Los Angeles, CA; Asst.
Research Ophthalmologist, 1997-1999
West Virginia University, Dept. of Biology, Morgantown, WV; Assistant Professor;
1999-2003
John R. Hawse, J. Fielding Hejtmancik, Joseph Horwitz and Marc Kantorow.
**Identification and functional gene clustering of global gene
expression differences between age-related cataract and clear human lenses
and aged clear human lenses. Experimental Eye Research 2004, 79, 3-9.
Marc Kantorow, John R. Hawse, Tracy L. Cowell, Sonia Benhamed, Gresin O.
Pizarro, Venkat Reddy and J. Fielding Hejtmancik.*Methionine sulfoxide reductase A is
important for lens cell viability and resistance to oxidative stress. Procedings of the
National Academy of Sciences USA, 2004, 101, 9654-9659.
John R. Hawse, James F. Hejtmancik, Quingling Huang, Nancy L. Sheets, Douglas A. Hosack,
Richard A. Lempicki, Joseph Horwitz and Marc Kantorow. *Identification and Functional
Clustering of Global Gene Expression Differences Between Human Age-Related Cataract and Clear
Lenses. Molecular Vision 2003, 7, 515-537.
Frank J. Secreto, A. Grover, M. Pacurari, Marc Kantorow, Ashok Bidwai, J.D. Blaha
and Phillip E. Keeting. Estrogen potentiates the combined effects of transforming growth factor
beta and tumor necrosis factor alpha on adult human osteoblast-like prostaglandin E2
biosynthesis. Calcif. Tissue Int. 2003, 73, 565-574.
Sumanta Goswami, Nancy Sheets, Jiri Zavadil, Bharesh Chuan, Marc Kantorow and
Ales Cvekl. **Spectrum and Range of oxidative stress responses of human lens
epithelial cells to H2O2 insult. Investigative Ophthalmology and Visual Science 2003, 44, 2084-2093.
John Hawse, Nancy Sheets, Brian Opperman, Venkat Reddy and Marc Kantorow.
Activation of methioneins and alpha-crystallin/sHSPs in human lens epithelial cells by
specific metals and the metal content of aging clear human lenses. Investigative Ophthalmology
and Visual Science 2003, 44, 672-680.
Nancy Sheets, Bharesh Chauhan, Eric Wawrousek, J. Fielding Hejtmancik, Ales Cvekl and
Marc Kantorow. Cataract- and lens-specific up-regulation of ARK Receptor tyrosine kinase
in Emory mouse cataract. Investigative Ophthalmology and Visual Science. 2002,
43,1870-1875.
Weiyan Zhang, Bharesh K. Chuhan, Kveta Cveklova, Marc Kantorow, and Ales Cvekl.
Identification of differentially expressed genes in mouse Pax6 heterozygous lenses.
Investigative Ophthalmology and Visual Science. 2002, 43 1884-1890.
Stephanie Runkle, Julie Hill, Marc Kantorow, Joseph Horwitz and Mason Posner.
Sequence and spatial expression of zebrafish alpha A-crystallin. Molecular Vision
2002, 8, 6-8.
Weiyan Zhang, John Hawse, QingLing Huang, Nancy Sheets, Kevin Miller, Joseph Horwitz
and Marc Kantorow. Decreased expression of ribosomal proteins in human age-related
cataract. Investigative Ophthalmology and Visual Science. 2002, 43, 198-204.
Weiyan Zhang, Kveta Cveklova, Brian Oppermann, Marc Kantorow, and Ales Cvekl.
Characterization of PAX6 and PAX6(5a) transcript and protein levels in adult human lens,
cornea, and retina. Molecular Vision. 2001 7,1-5.
Brian Oppermann, Weiyan Zhang, Kristine Magabo and Marc Kantorow. Identification
and spatial analysis of metallothioneins expressed by the adult human lens. Investigative
Ophthalmology and Visual Science. 2001, 42,188-193.
Kristine Magabo, Joseph Horwitz, Joram Piatigorsky and Marc Kantorow. Expression
of betaB2-crystallin mRNA and protein in retina, brain and testis. Investigative
Ophthalmology and Visual Science. 2000 41, 3056-3060.
Young-Sheng Xu, Marc Kantorow, Janine Davis and Joram Piatigorsky. Evidence for
Gelsolin as a corneal crystallin in zebrafish. Journal of Biological Chemistry 2000,
275, 24645-24652.
Ignacio Rodriquez, Ernesto Moreira, Dean Bok and Marc Kantorow.
Osteonectin/SPARC is secreted by RPE and localized to the outer plexiform layer of the
monkey retina. Investigative Ophthalmology and Visual Science. 2000; 41, 2438-2444.
Marc Kantorow, Quingling Huang, Xian-Jie Yang, E. Helene Sage, Kristine S.
Magabo, Kevin M. Miller and Joseph Horwitz. Increased Expression of osteonectin/SPARC
mRNA and protein in age-related human cataracts and spatial expression in the normal
human lens. Molecular Vision 2000;6, 24-29.