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College of Biomedical Science
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Department of Basic Science
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Wei, Jianning Dr.
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- B.S., University of Science and Technology of China, Hefei Anhui, P.R.China,1999
- Ph.D., University of Kansas, Lawrence, KS, USA, 2003
- Postdoctoral Fellow, Florida Atlantic University, Boca Raton, FL, USA, 2003-2005
- To investigate protein-protein interaction using a combination of biochemical methods and mass spectrometry.
- Molecular mechanisms of age-related neurodegenerative diseases, such as Alzheimer's disease, Huntington's disease.
- The physiological function of Huntington interaction protein (HIP14) as a neuronal palmitoyl transferase.
- 2006, Research Assistant Professor, Department of Biomedical Science, Florida Atlantic University
- Wei, J.N., Lin, C-H., Wu, H., Jin, Y., Lee, Y-H., and Wu, J-Y. Activity Dependent Cleavage of Brain Glutamic Acid Decarboxylase 65 by Calpain J. Neurochem. 98(5), 1688-95. (2005).
- Wei, J.N., and Wu, J-Y. Structural and Functional Analysis of Cysteine Residues in Human Glutamate Decarboxylase 65 (GAD65) and GAD67. J. Neurochem. 93 (3), 624-633.(2005).
- Jin, H., Sha, D., Wei, J. N., Davis, K.M., Wu, H., Jin, Y., and Wu, J-Y. Effect of apocalmodulin on recombinant human brain glutamic acid decarboxylase. J. Neurochem. 92, 739-48.(2005).
- Sha, D., Wei, J.N., Wu, H., Jin, Y., and Wu, J-Y. Molecular cloning, expression, purification, and characterization of shorter forms of human glutamic decarboxylase 67 in an E. coli expression system. Brain Res. Mol. Brain Res. 136 (1-2), 255-61.(2005).
- Wu, H., Jin, Y., Wei, J.N., Jin, H., Sha, D., and Wu, J-Y. Mode of action of taurine as a neuroprotector. Brain Res. 1038 (2), 123-131.(2005)
- Wei, J.N., Davis, K.M., Wu, H., and Wu, J-Y. Protein phosphorylation of human brain glutamic acid decarboxylase (GAD)65 and GAD67 and its physiological implications. Biochemistry 43, 6182-89. (2004)
- Wei, J.N., Jin, Y., Wu, H., and Wu, J-Y. Identification and functional analysis of truncated human glutamic acid decarboxylase 65. J. Biomed. Sci. 10, 617-24. (2003).
- Sha, D., Wei, J.N., Jin, H., Wu, H., Osterhaus, G. L., and Wu, J-Y. Effect of taurine on regulation of GABA and acetylcholine biosynthesis. Adv Exp Med Biol. 526, 499-505.(2003)
- Chen, R., Wei, J.N., Fowler, S.C., and Wu, J.Y. Demonstration of functional coupling between dopamine synthesis and its packaging into synaptic vesicles. J. Biomed. Sci. 10, 774-81. (2003)
- Jin, H., Wu, H., Osterhaus, G., Wei, J.N., Davis, K., Sha, D., Floor, E., Hsu, C.C., Kopke, R.D., and Wu, J.Y. Demonstration of functional coupling between gamma-aminobutyric acid (GABA) synthesis and vesicular GABA transport into synaptic vesicles. Proc. Natl. Acad. Sci. USA 100, 4293-98. (2003).
- Zhu, M.Z., Wei, J.N., Wu, Q.H., Zheng, X.Q., and Guo, Q.X. A synthetic study of neutral and cationic cholesteryl derivatives as gene vectors. Syn. Comm. (USA) 30(13), 2325. (2000)
- 12. Zhu, M.Z., Wei, J.N., Wu, Q.H., Zheng, X.Q., and Guo, Q.X. Synthesis of novel cationic lipids bearing cholesteryl groups as gene vectors. Chinese Chemical Letter 11(7), 577-580.(2000)
- Zhu, M.Z., Wei, J.N., Wu, Q.H., Zheng, X.Q., Guo, Q.X., and Liu, Y.C. Biodegradable cationic lipids bearing cholesteryl groups: A synthetic study. Journal of Xiamen University 38 (sup), 547. (in Chinese). (1999)
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