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College of Biomedical Science
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Department of Clinical Science and Medical Education Faculty
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Dorey, Kathleen Dr.
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- B.A., cum laude SUNY at Buffalo, 1966.
- M.A., University of Massachusetts, 1969.
- Ph.D., Georgetown University, 1975.
- Postdoctoral Fellowship University of Southern California,1975-1978.
- Age-related macular degeneration (AMD).
- Role of carotenoids in age-related diseases, particularly AMD.
- Neovascularization
- R&D; Consulting, Senior Scientist, 2000-2004.
- Massachusetts Institute of Technology, Visiting Professor, 1998-1999
- Schepens Eye Research Institute & Dept. Ophthalmology, Harvard Medical School Asst. Scientist, Associate Scientist, 1985-1998
- Doheny Eye Foundation (University of Southern California) Asst. Professor Ophthalmology, Anatomy and Cell Biology, 1980-85
- Southern Illinois University Asst. Professor of Anatomy 1978-1980
- Dorey C.K., Granata, L., Nichols, C.R., Cheng, K.M., Craft, N.E. Dietary modulation of lens zeaxanthin in quail. Exp Eye Res. (in process).
- Craft, N.E., Haitema, T.B., Garnett, K.M., Fitch, K.A., Dorey, C.K. Carotenoid, tocopherol and retinol concentrations in elderly human brain. J. Nutrition, Health and Aging, 8: 156-62, 2004.
- Pang, J., Cheng, M., Stevenson, D., Trousdale, M.D., Dorey, C.K., and Blanks, J.C. Adenoviral-mediated gene transfer to retinal explants during development and degeneration. Exp. Eye. Res. 79: 180-201, 2004.
- Thomson, L.R., Toyoda, Y., Langner, A., Delori, F.C., Garnett, K.M., Z-Y, Wong, Nichols, C.R., Cheng, K.M., Craft, N.E. and Dorey, C.K. Long term supplementation with dietary zeaxanthin reduces photoreceptor death in light-damaged quail. Exp. Eye Res. 75(5):529-542, 2002.
- Thomson, L.R., Toyoda, Y., Langner, A., Delori, F.C., Garnett, K.M., Nichols, C.R., Cheng, K.M., and Dorey, C.K. Light-induced photoreceptor cell death in quail is prevented by elevated retinal zeaxanthin. Invest. Ophthalmol. Vis. Sci. 43(11)3548-49, 2002.
- Toyoda, Y., Thomson, L.R., Langner, A., Craft, N.E., Garnett, K.M., Nichols, C.R., Cheng, K.M., and Dorey, C.K. Effect of dietary zeaxanthin on tissue distribution of zeaxanthin and lutein in quail. Invest. Ophthalmol. Vis. Sci. 43: 1210-1221, 2002.
- Delori, F., Goger, D. and Dorey, C.K. Accumulation of lipofuscin in the retinal pigmented epithelium; Age relationship and spatial distribution in normal subjects. Invest. Ophthalmol. Vis. Sci., 45: 1855-1866, 2001.
- Chau, K-Y., Munshi, N., Keane-Myers, A., Cheug-Chau, K-W., Tai, A.K-F., Manfioletti, G., Dorey, C.K., Thanos, D., Zack, D.J., and Ono, S.J. The architectural transcription factor HMG1(Y) participates in photoreceptor-specific gene expression. J. Neuroscience 20:7317-7324, 2000.
- Hasebe, Y., Thomson, L., Dorey, C.K. Pentoxifylline inhibits intraretinal angiogenesis in neonatal rats. Invest. Ophthalmol. Vis. Sci. 41:2774-2778, 2000.
- Delori, F.C., Fleckner, M.R., Goger, D.G., Weiter, J.J., Dorey C.K. Autofluorescence Distribution associated with drusen in AMD. Invest. Ophthalmol. Vis. Sci. 41:496-504, 2000.
- Kunert KS, Fitzgerald MEC, Thomson L, Dorey, C.K. Microglia increase as photoreceptors decrease in the aging avian retina. Current Eye Research, 18:440-447, 1999.
- Delori, FC and Dorey, C.K., In vivo technique for autofluorescent lipopigments. Methods Mol Biol.108:229-43, 1998.
- Armstrong D, Ueda T, Ueda T, Browne R, Al_Jada A, Fukuda S, Spengler R, Chou R, Hartnett ME, Buch P, Dandona P, Sasisekharan R, Dorey, C.K. Hydroperoxide stimulates expression of TNFa,VEGF and PDGF and retinal neovascularization in rabbit retina. Angiogenesis 2 (1): 95-108 1998.
- Ueda T, Ueda T, Fukuda S, Browne R., Jenis E, Spengler R, Chou R, Buch P, Al-Jada A, Dandona P, Dorey, C.K., Sasisekharan R, Armstrong D. Lipid hydroperoxides and TNFa and VEGF in a corneal model of neovascularization. Effect of TNFa inhibition. Angiogenesis; 1(2): 174-184, 1997
- Douki T, Lee S, Dorey, C.K., Floote TJ., Deutsch TF, Doukas AG. Stress-wave-induced injury to retinal pigment epithelium cells in vitro. Lasers in Surgery & Medicine, 19: 249-259, 1996
- Dorey, C.K., Aouididi S, Brown L, Xavier Reynaud and Dvorak HC. Correlation of vascular permeability factor/vascular endothelial growth factor with extraretinal neovascularization in the rat. Arch. Ophthalmol ; 114:1210-1218.1996.
- Delori FC, Staurenghi G, Arend O, Dorey, C.K., Goger D, Weiter JJ. In-vivo measurement of lipofuscin in patients with Stargardts disease / Fundus Flavimaculatus. Invest. Ophthalmol. Vis. Sci. 36: 2327-2331, 1995.
- Reynaud X and Dorey, C.K. Episodes of Hypoxia Induce Neovascularization in the Rat Retina. Invest. Ophthalmol. Vis. Sci. 34:3169-77, 1994.
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