College of Medicine / About / Departments / Biomedical Science Department / Xupei Huang, M.D., PhD.


Charles E. Schmidt College of Medicine
Florida Atlantic University
777 Glades Road
Boca Raton, FL 33431



Professor of Biomedical Science

Tel. (561) 297-2443


Xupei Huang, M.D., Ph.D., serves as Professor of Biomedical Science in the Charles E. Schmidt College of Medicine. Dr. Huang received his medical training in Nanjing Medical University, China and Ph.D. training in Biochemistry from University of Paris XII, France. Working at FAU since 2001, Dr. Huang and his group investigate the mechanisms and treatment of cardiomyopathies and heart failure and have published over 80 peer-reviewed research papers in the field. Dr. Huang serves as Associate Editor for academic journal Cardiology. Dr. Huang teaches Cardiovascular System for medical students in the college. 


  • 1985: M.D., Nanjing Medical University, Nanjing, China
  • 1992: Ph.D., Biochemistry, University of Paris XII, France

  • 2001-Present: Charles E. Schmidt College of Medicine, Florida Atlantic University, Boca Raton, Florida
  • 1996-2001: Research Assistant Professor, Texas A&M University, College Station, Texas

  • Zhang L., C. Nan, Y. Chen, J. Tian, P. Jean-Charles, C. Getfield, X. Wang, X.P. Huang. Calcium desensitizer catechin reverses diastolic dysfunction in mice with restrictive cardiomyopathy. Archive of Biophys. Biochem. 573:69-76, 2015.
  • Ira Gelb and Xupei Huang. Update in pediatric infective endocarditis. Cardiology, 128:86-87, 2014.
  • Chen G., C.Nan, J. Tian, P. Jean-Charles, Y. Li, H. Weissbach, X.P. Huang. Protective effects of taurine against oxidative stress in the heart of MsrA knockout mice. J. Cell. Biochem. 113:3559-3566, 2012.
  • Jean-Charles P., Y. Li, C. Nan, X.P. Huang. Insights into restrictive cardiomyopathy from clinical and animal studies. J Geriatr. Cardiology. 8:168-183, 2011.
  • Li Y., P.Y. Jean-Charles, C. Nan, J. Pinto, Y. Wang, J. Liang, G. Wu, J. Tian, H. Feng, J.D. Potter, J.P. Jin, X.P. Huang. Correcting diastolic dysfunction by Ca2+ desensitizing troponin in a transgenic mouse model of restrictive cardiomyopathy. J. Cell Mol. Cardiology. 49:402-411, 2010.
  • Liu J., J. Du, C. Zhang, JW. Walker, XP. Huang. Troponin I deficiency causes impaired cardiac relaxation and heart failure in mice. Am. J Physiol. Heart Circ Physiol. 293:H1273-H1281, 2007.
  • Yuejin Li, Lei Zhang, Pierre-Yves Jean-Charles, Changlong Nan, Guozhen Chen, Jie Tian, J.-P., Jin, Ira J. Gelb, Xupei Huang .Dose-dependent diastolic dysfunction and early death in a mouse model with cardiac troponin mutations, J. Mol. Cell. Cardiology, 62:227-236, 2013.
  • Du J., J. Liu, H.Z. Feng, M.M. Houssain, N. Gobara, C. Zhang, Y. Li, P.Y. Jean-Charles, J.P. Jin, X.P. Huang. Impaired relaxation is the main manifestation in transgenic mice expressing a restrictive cardiomyopathy mutation, R193H, in cardiac TnI. Am J Physiol Heart Circ Physiol. 294: H2604-H2613, 2008.
  • Huang XP, Walker JW. Myofilament anchoring of protein kinase C in cardiac myocytes.  J Cell Science 117:1971-1978, 2004.
  • Huang XP, Pi YQ, Lee KJ, Henkel AS, Gregg RG, Powers PA, Walker JW. Cardiac troponin I gene knockout: A mouse model of myocardial troponin I depletion. Circ Res. 84(1):1-8, 1999. 

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Research Interests

  • Intracellular signal pathways, protein phosphorylation and cellular function
  • Gene expression profiling and gene regulation in the heart
  • Functional evaluation of cardiac genes
  • Transgenic and gene knockout animal models

Last Modified 11/8/16