Charles E. Schmidt College of Medicine
Florida Atlantic University
777 Glades Road
Boca Raton, FL 33431
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Severe malaria syndromes caused by Plasmodium falciparum kill about 1 million African children each year. Severe malaria is mainly due to adhesion of parasite-infected erythrocytes in deep vascular beds in various organs mediated by the PfEMP1 family of parasite proteins expressed on the erythrocyte surface. The Oleinikov laboratory, under the leadership Andrew Oleinikov, Ph.D., Associate Professor of Biomedical Science, studies malaria parasite biology and virulence factors, and anti-malarial defense mechanisms. Primary research objectives include understanding immunity to severe malaria in children and molecular mechanisms of pregnancy malaria, developing a pregnancy malaria vaccine, and developing various technologies for malaria research and treatment including identification of new anti-malarial drugs.