Charles E. Schmidt College of Medicine
Florida Atlantic University
777 Glades Road
Boca Raton, FL 33431

561-297-4828

JIANNING WEI, Ph.D.

Associate Professor of Biomedical Science


wei
CONTACT
jwei@health.fau.edu
Tel. (561) 297-0002

 
 

 

Jianning Wei, Ph.D. is an associate professor of biomedical science.

 

  • 1999: B.S., Organic Chemistry, University of Science and Technology of China, Hefei Anhui, P.R.China
  • 2003: Ph.D., Biochemistry, University of Kansas, Lawrence, KS, USA,
  • 2003-2005: Fellow, Florida Atlantic University, Boca Raton, FL, USA 

  • 2013-Present: Associate Professor, Department of Biomedical Science, Charles E. Schmidt College of Medicine, Boca Raton, FL.
  • 2008-2010: Affiliated Assistant Professor of Biochemistry and Molecular Biology, University of Miami Miller School of Medicine.
  • 2006-2013: Assistant Professor, Department of Biomedical Science, Charles E. Schmidt College of Medicine, Boca Raton, FL.
  • 2006: Research Assistant Professor, Department of Biomedical Science, Charles E. Schmidt College of Science, Boca Raton, FL.
  • 2003-2005: Postdoctoral Fellow , Department of Biomedical Science, Charles E. Schmidt College of Science, Florida Atlantic University, Boca Raton, FL.

 

  • Erie, C., Sacino, M., Houle, L., Lu, M., Wei, J. (2015). Altered lysosomal positioning affects lysosomal functions in a cellular model of Huntington's disease. Eur J Neurosci. doi: 10.1111/ejn.12957. [Epub ahead of print] PMID: 25997742
  • McCollum, M., Leon, R., Rush, D., Guthrie, K., Wei, J. (2013) Striatal oligodendrogliogenesis and neuroblast recruitment is increased in the R6/2 mouse model of Huntington's disease. Brain Res. pii: S0006-8993(13)00572-6. doi: 10.1016/j.brainres.2013.04.030. [Epub ahead of print]
  • Rush, D., Leon, R., McCollum, M., Treu, R., Wei, J. (2012) Palmitoylation and trafficking of GAD65 is impaired in a cellular model of Huntington disease. Biochem J. 442(1) 39-48.
  • McGreal, R.S., Kantorow, W.L., Chauss, D.C., Wei, J., Brennan, L.A., Kantorow, M. (2012) αB-crystallin/sHSP protects cytochrome c and mitochondrial function against oxidative stress in lens and retinal cells. Biochim Biophys Acta. 820(7), 921-30.
  • Krishnamoorthy, S., Ma, Z., Zhang, G., Wei, J., Auerbach, SB., Tao, R. (2010) Involvement of 5-HT(2A) Receptors in the Serotonin (5-HT) Syndrome caused by Excessive 5-HT Efflux in Rat Brain. Basic Clin Pharmacol Toxicol. 107 (4), 830-41.
  • Leon, R., Bhagavatula, N., Ulukpo, O., McCollum, M., Wei, J. BimEL as a possible molecular link between proteasome dysfunction and cell death induced by mutant huntingtin. Eur J Neurosci. 31, 1915-1925. 2010.
  • McCollum, M., Ma, Z., Cohen, E., Leon, R., Tao, R., Wu, J-Y., Maharaj, D., Wei, J. Post-MPTP treatment with granulocyte colony-stimulating factor improves nigrostriatal function in the mouse model of Parkinson's disease. Mol Neurobiol. 41(2-3), 410-9. 2010.
  • Wei, J.N., Lin, C-H., Wu, H., Jin, Y., Lee, Y-H., and Wu, J-Y. Activity Dependent Cleavage of Brain Glutamic Acid Decarboxylase 65 by Calpain J. Neurochem. 98(5), 1688-95. (2005).

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Research Interests

  • To investigate protein-protein interaction using a combination of biochemical methods and mass spectrometry.
  • Molecular mechanisms of age-related neurodegenerative diseases, such as Alzheimer's disease, Huntington's disease.
  • The physiological function of Huntington interaction protein (HIP14) as a neuronal palmitoyl transferase.


Last Modified 11/8/16